JC Gumbart (PI)


Assistant Professor of Physics

  • Director’s Postdoctoral Fellow, Argonne National Laboratory, (2011-2012)
  • Ph.D. in Physics, University of Illinois, Urbana-Champaign (2009)
  • B.S. in Physics and Mathematics, Western Illinois University (2003)

(My CV – PDF, last updated May 2016)



  • Fall 2015: Intro Physics I (PHYS 2211)
  • Fall 2015: Senior Seminar I (PHYS 4601)
  • Fall 2014: Biophysics (PHYS 4251)
  • Fall 2013: Biophysics (PHYS 4251)

Representative Publications

  1. Reconciling the roles of kinetic and thermodynamic factors in membrane-protein insertion.
    James C. Gumbart, Ivan Teo, Benoit Roux, and Klaus Schulten. Journal of the American Chemical Society, 135:2291-2297, 2013.
  2. Standard binding free energies from computer simulations: What is the best strategy?
    James C. Gumbart, Benoit Roux, and Christophe Chipot. Journal of Chemical Theory and Computation, 9:794-802, 2013.
  3. Structural basis for iron piracy by pathogenic Neisseria.
    Nicholas Noinaj, Nicole C. Easley, Muse Oke, Naoko Mizuno, James Gumbart, Evzen Boura, Ashley N. Steere, Olga Zak, Philip Aisen, Emad Tajkhorshid, Robert W. Evans, Andrew R. Gorringe, Anne B. Mason, Alasdair C. Steven, and Susan K. Buchanan. Nature, 483:53-58, 2012.
  4. Cryo-EM structure of the ribosome-SecYE complex in the membrane environment.
    Jens Frauenfeld, James Gumbart, Eli O. van der Sluis, Soledad Funes, Marco Gartmann, Birgitta Beatrix, Thorsten Mielke, Otto Berninghausen, Thomas Becker, Klaus Schulten, and Roland Beckmann. Nature Structural & Molecular Biology, 18:614-621, 2011.
  5. Free-energy cost for translocon-assisted insertion of membrane proteins.
    James Gumbart, Christophe Chipot, and Klaus Schulten. Proceedings of the National Academy of Sciences, USA, 108:3596-3601, 2011.
  6. Structure of monomeric yeast and mammalian Sec61 complexes interacting with the translating ribosome.
    Thomas Becker, Shashi Bhushan, Alexander Jarasch, Jean-Paul Armache, Soledad Funes, Fabrice Jossinet, James Gumbart, Thorsten Mielke, Otto Berninghausen, Klaus Schulten, Eric Westhof, Reid Gilmore, Elisabet C. Mandon, and Roland Beckmann. Science, 326:1369-1373, 2009.
Contact Info
e-mail: gumbart // at // physics.gatech.edu
phone: 404-385-0797
fax: 404-894-9958
office: W207 Howey Physics Building
mail: School of Physics, 837 State Street, Atlanta, GA 30332-0430