Curtis and JC’s work on simulating the transporter BtuB in its native outer-membrane environment is now a featured article in the latest issue of Biophysical Journal. Congrats Curtis!
Author Archives: gumbart
The noise is the mechanism
At the NSF iPoLS meeting at Harvard, which JC, Sunny, and Curtis are presenting at, one of the best talks was given by Nigel Goldenfeld (UIUC).
The homochirality of certain biological molecules, especially amino acids in proteins (all L form) and sugars (all D form), has long been a mystery in biology. What processes in early evolution would have led to biological systems using only one form? Hypotheses have included autocatalytic mechanisms as well as even extraterrestrial origins. However, Goldenfeld has recently shown that there’s been a missing ingredient in many of these: the role of noise! Biological systems operate far from equilibrium, and we often find that noise (“stochasticity”) is a beneficial, even critical element, rather than a detrimental background to be minimized. Goldenfeld and colleagues showed that by incorporating two simple principles, self-replication and noise, homochirality can be established.
See a news story here and the original paper here.
Back to the mountains!
JC and Karl just got back from the Molecular Biophysics of Membranes meeting in Snowmass, CO. Along with some great science at the meeting, we also got great views, such as the one of Crater Lake above!
Roux Reunion in Halifax
JC just got back from the Canadian Society for Chemistry meeting in Halifax, Nova Scotia. While Halifax is a great summer destination, JC was there in particular for a reunion of former students, postdocs, and (current) friends of Benoit Roux organized by Chris Rowley (Memorial University, lower right of the picture). It was a fantastic few days full of good science and great company.
Congrats Alex!
Alex Covington, senior physics student, won the “Roger M. Wartell, Ph.D., and Stephen E. Brossette, M.D., Ph.D., Award for Multidisciplinary Studies in Biology, Physics, and Mathematics” from the College of Sciences at Georgia Tech. It comes with a $3,000 scholarship and a certificate to be awarded at a ceremony on April 22. Alex won for his tireless efforts on integrating a lightweight version of the molecular dynamics program NAMD into the visualization program VMD. Such a tool would provide numerous benefits for, e.g., structure completion, system building, and education.