In collaboration with the labs of Tom Rapoport and Chris Akey, we have determined a new cryo-EM based structure of membrane-protein insertion intermediate. See the article here.
Our work on the BamA structure in collaboration with the lab of Susan Buchanan at NIH is now out in Nature! See the news article and the paper.
Curtis has received a GAANN fellowship for 2013-2014 as part of the Molecular Biophysics Training Program. Congratulations!
JC just returned from two back-to-back meetings in Snowmass, CO. He presented work on small-helix partitioning in membranes at the first meeting on Free Energy Methods and structures of BamA and a new complex between SecY and a nascent chain at the second meeting on Membrane Proteins. Not all the time was spent in front of a screen though, as the picture to the right clearly shows!
Three recent papers highlight the close connection between the Gumbart lab and experimental labs focusing on bacteria-specific systems. These systems include
See the publications for more details!